Are Selected Cytokines and Epstein–Barr Virus DNA Load Predictors of Hepatological Complications of Epstein–Barr Virus Infection in Children?

نویسندگان

چکیده

The aim of the study was to evaluate tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6), soluble intracellular adhesion molecules 1 (s-ICAM-1) and Epstein–Barr virus (EBV) DNA load levels as predictors hepatological complications EBV infection in children. group consisted 54 children aged one eighteen years, who were hospitalised from December 2018 31 2020 Department Paediatrics, Infectious Diseases Hepatology had course serologically molecularly confirmed infection. It shown that IL-6, TNF-α, s-ICAM-1 concentrations highest patients with hepatitis biliary pole damage. Higher viremia positively correlated increased C-reactive protein (CRP) TNF-α leukocyte, lymphocyte, monocyte counts. Increases lymphocyte counts observed along increases gamma-glutamyl transpeptidase (GGTP) activity. Increased may indicate risk concomitant damage during

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ژورنال

عنوان ژورنال: Journal of Clinical Medicine

سال: 2023

ISSN: ['2077-0383']

DOI: https://doi.org/10.3390/jcm12196158